Postoperative changes in BAL fluid
| Preoperative BALF | Postoperative BALF | p Value | |
|---|---|---|---|
| Total Protein, μg/mL (IQR) | 118 (68.0–188) | 187 (94.3–264) | 0.029 |
| Leucocyte count, millions/mL (IQR) | 0.10 (0.07–0.17) | 0.18 (0.09–0.31) | 0.012 |
| Macrophages/monocytes, % (IQR) | 93 (75–96) | 84 (45–92) | 0.232 |
| Neutrophils, % (IQR) | 4 (2–23.5) | 13 (3–49) | 0.176 |
| Lymphocytes, % (IQR) | 2 (1–3) | 3 (1–4) | 0.259 |
| Other leucocyte, % (IQR) | <1 (0) | <1 (0) | 1 |
| IL-10, pg/mL (IQR) | 0 (0.1–0.99) | 0.77 (0–2.07) | 0.018 |
| IL-1β, pg/mL (IQR) | 1.14 (0–7.59) | 6.22 (1.50–24.58) | 0.002 |
| IL-6, pg/mL (IQR) | 4.67 (1.08–10.71) | 17.71 (4.29–45.7) | <0.0005 |
| IL-8, pg/mL (IQR) | 114 (61.6–275) | 258 (95.7–733) | 0.017 |
BAL was always performed in the non-operated lung. The preoperative and postoperative BALs were performed in different lung segments. Data are presented as median and IQR, while statistical analysis was by paired Student t test. Total protein and differential leucocyte counts, n=33. Total leucocyte count, n=36. Cytokine analysis, n=35.
BAL, bronchoalveolar lavage; BALF, BAL fluid.