Univariate and multivariate analysis of clinical parameters to differentiate between reactive and pathological lymphadenopathy
| Clinical factor | Measure | OR* | 95% CI | p Value |
|---|---|---|---|---|
| Univariate analysis | ||||
| Age | Years | 1.07 | 1.04 to 1.11 | 0.00004 |
| Sex | M:F | 1.93 | 0.84 to 4.41 | 0.12 |
| Ethnicity | White British vs other | 4.65 | 1.76 to 12.26 | 0.002 |
| Symptoms | Yes:no | 1.56 | 0.47 to 5.16 | 0.46 |
| Mean (no) | 0.84 | 0.57 to 1.24 | 0.39 | |
| Weight loss (yes:no) | 0.16 | 0.05 to 0.47 | 0.001 | |
| Fevers (yes:no) | 0.10 | 0.02 to 0.45 | 0.003 | |
| Comorbidity | ≥1 (yes:no) | 27.86 | 9.49 to 81.77 | <0.000001 |
| Lymph nodes | Number of stations enlarged | 0.73 | 0.54 to 0.99 | 0.041 |
| Mean diameter largest | 0.69 | 0.59 to 0.79 | <0.000001 | |
| Multivariate analysis | ||||
| Age | Years | 1.07 | 1.01 to 1.13 | 0.033 |
| Comorbidity | ≥1 (yes:no) | 9.49 | 2.20 to 41.04 | 0.003 |
| Lymph nodes | Mean diameter largest | 0.70 | 0.59 to 0.83 | 0.00004 |
*Likelihood of reactive lymphadenopathy.