Comparison of characteristics, admission findings and baseline QoL of ventilated and non-ventilated patients
| Variable | Ventilated (n=82) | Non-ventilated (n=101) | p Value |
|---|---|---|---|
| Clinical data | |||
| Age (years) | 69.3 (9.2) | 68.7 (8.8) | 0.63 |
| Female (%) | 67.1 | 51.5 | 0.036 |
| Hospitalisations in previous year (median, IQR) | 0 (0 to 2) | 0 (0 to 1) | 0.52 |
| Previously received assisted ventilation (%) | 41.5 | 9.9 | <0.001 |
| Previous pulmonary rehabilitation (%) | 14.6 | 18.8 | 0.55 |
| FEV1% predicted | 36.8 (18.3) | 42.9 (16.1) | 0.018 |
| eMRCD (median, IQR) | 4 (4 to 5a) | 4 (3 to 4) | <0.001 |
| Cor pulmonale (%) | 18.3 | 6.9 | 0.023 |
| LTOT (%) | 30.5 | 5.9 | <0.001 |
| Charlson Comorbidity Index (median, IQR) | 1 (1 to 2) | 2 (1 to 2) | 0.14 |
| BMI (kg/m2) | 26.4 (7.2) | 25.9 (6.8) | 0.62 |
| CXR consolidation (%) | 28.0 | 28.7 | 1 |
| pH (median, IQR) | 7.29 (7.24 to 7.34) | 7.43 (7.39 to 7.47) | <0.001 |
| paO2, kPa (median, IQR) | 8.4 (6.6 to 12.2) | 8.3 (7.2 to 10.0) | 0.98 |
| paCO2, kPa (median, IQR) | 9.3 (7.6 to 11.6) | 5.3 (4.9 to 6.5) | <0.001 |
| Length of stay (days) | 10 (7 to 15) | 7 (4 to 11) | <0.001 |
| DECAF (median, IQR) | 2 (1 to 2) | 1 (0 to 2) | <0.001 |
| Discharge QoL | |||
| SGRQ* | |||
| Symptoms | 65.2 (49.3 to 80.9) | 71.5 (60.7 to 83.0) | 0.026 |
| Activity | 82.9 (72.7 to 92.5) | 85.8 (66.8 to 92.5) | 0.97 |
| Impacts | 50.3 (38.1 to 68.8) | 51.1 (36.0 to 62.9) | 0.64 |
| Total | 62.5 (51.9 to 73.6) | 63.1 (52.3 to 73.5) | 0.94 |
| CRQ† | |||
| Dyspnoea | 2.8 (2.2 to 3.8) | 2.8 (2 to 4) | 0.57 |
| Emotional function | 2 (1.3 to 3) | 3.7 (2.7 to 4.8) | 0.061 |
| Fatigue | 3.3 (2.1 to 4.9) | 2.5 (1.8 to 3.2) | 0.17 |
| Mastery | 2.8 (2 to 4.1) | 3.3 (2.3 to 4.5) | 0.14 |
| HADS* | |||
| Anxiety | 8.5 (4 to 14) | 8 (4.5 to 12.5) | 0.35 |
| Depression | 6 (3 to 10) | 6 (3 to 8) | 0.50 |
| NEADL† | |||
| 31 (19 to 41) | 38 (32 to 47.5) | 0.001 | |
Values quoted are mean (SD) unless otherwise stated.
*Lower scores indicate better QoL.
†Higher scores indicate better QoL.
BMI, body mass index; CRQ, Chronic Respiratory Disease Questionnaire; DECAF, Dyspnoea, eosinopenia, consolidation, acidosis, atrial fibrillation prognostic score; FEV1, forced expiratory volume in 1 s; HADS, Hospital Anxiety and Depression Scale; NEADL, Nottingham Extended Activity of Daily Living Scale; SGRQ, St George's Respiratory Questionnaire; QoL, quality of life.