Association between self-reported chronic cough and breathlessness symptoms and self-reported health, lipids, BNP and body mass index
| No respiratory symptoms | Chronic cough and breathlessness | Test for trend | |||
|---|---|---|---|---|---|
| ≤Grade 2 breathlessness | ≥Grade 3 breathlessness | ||||
| Coefficient (95% CI) | |||||
| SF-12 PCS (n=967) | Model 1 | 1 (ref) | −3.49 (−4.80 to −2.18) | −11.56 (−13.78 to −9.33) | p<0.001 |
| Model 2 | 1 (ref) | −3.60 (−4.95 to −2.25) | −11.58 (−13.83 to −9.34) | p<0.001 | |
| SF-12 MCS (n=967) | Model 1 | 1 (ref) | −1.36 (−2.88 to 0.16) | −5.97 (−8.55 to −3.39) | p<0.001 |
| Model 2 | 1 (ref) | −1.33 (−2.90 to 0.24) | −5.90 (−8.51 to −3.29) | p<0.001 | |
| Total cholesterol (n=916) | Model 1 | 1 (ref) | −0.16 (−0.33 to 0.02) | −0.25 (−0.55 to 0.05) | p=0.02 |
| Model 2 | 1 (ref) | −0.13 (−0.31 to 0.06) | −0.23 (−0.53 to 0.08) | p=0.06 | |
| HDL-C (n=916) | Model 1 | 1 (ref) | −0.05 (−0.13 to 0.03) | −0.10 (−0.23 to 0.03) | p=0.07 |
| Model 2 | 1 (ref) | −0.08 (−0.16 to 0.002) | −0.13 (−0.26 to 0.01) | p=0.01 | |
| Log triglycerides (n=900) | Model 1 | 1 (ref) | −0.02 (−0.11 to 0.07) | 0.02 (−0.14 to 0.17) | p=0.88 |
| Model 2 | 1 (ref) | 0.01 (−0.08 to 0.11) | 0.04 (−0.11 to 0.20) | p=0.56 | |
| Log BNP (n=908) | Model 1 | 1 (ref) | 0.16 (0.003 to 0.31) | 4.14 (0.16 to 0.67) | p=0.001 |
| Model 2 | 1 (ref) | 0.11 (−0.05 to 0.26) | 0.37 (0.12 to 0.63) | p=0.006 | |
| Body mass index (n=978) | Model 1 | 1 (ref) | 0.37 (−0.38 to 1.12) | 1.86 (0.60 to 3.12) | p=0.01 |
| Model 2 | 1 (ref) | 0.95 (0.19 to 1.70) | 2.29 (1.05 to 3.53) | p<0.001 | |
Model 1: adjusted for age and education.
Model 2: model 1 + smoking status.
BNP, B-type natriuretic peptide; HDL-C, high-density lipoprotein cholesterol; MCS, mental health component score; PCS, physical health component score; SF-12, 12-Item Short-Form Health Survey.