Table 1

Registry organisation: committee roles and responsibilities

Committee	Key roles and responsibilities
Executive Committee	▸ Scientific leadership of the registry ▸ Assume responsibilities from all other Committees after completion of the funded registry period
Steering Committee	▸ Programme development ▸ Operational oversight of registry conduct, including monitoring of site performance ▸ Protocol amendments ▸ Generate ideas/topics for publications
Publications Committee	▸ Review proposed registry analyses and recommend approval to Executive Committee ▸ Collaborate with the Biomarker Committee on proposed analyses and publications ▸ Ensure adherence to international standards on criteria for authorship of scientific publications ▸ Review all publications prior to submission
Biomarker Committee	▸ Evaluate proposed studies involving use of samples collected in the registry for feasibility and scientific value ▸ Assess studies’ needs and implement efficient use of available samples, including prioritisation