Table 4

Validation analyses for ANGPTL4 as independent predictor of left ventricular mass in chronic obstructive pulmonary disease

LV mass
Coefficient B (95% CI)Standardized βp ValueTotal R2
Unadjusted models
 log-ANGPTL4, ng/mL17.8 (8.2 to 27.4)0.30<0.0010.089
Adjusted models*
 log-ANGPTL4, ng/mL16.1 (6.8 to 25.4)0.27<0.0010.345
  • Two separate linear regression analyses are shown for the validation cohort of patients with COPD. ANGPTL4 was log-transformed to obtain a normal distribution.

  • *The adjusted regression models included the same adjustments like in the model for NT-proBNP (see tables 2 and 3), that is, age, sex, body mass index, smoking status, the metabolic syndrome, LDL cholesterol, FEV1, hs-CRP and history of CAD.