Differences of serum levels of immunoglobulins in patients with CAP according to the site of care on the first day of medical consultation
| Serum levels of immunoglobulins (mg/dL) | Site of care of patients with CAP | p Value three study groups | p Value ICU vs non-ICU groups | |||
|---|---|---|---|---|---|---|
| Ambulatory (n=54) | Hospital ward (n=173) | ICU (n=191) | Non-ICU (n=227) | |||
| IgG, total | 1110 (889–1350) | 986.5 (768.5–1175) | 908 (682–1300) | 1010 (810–1210) | 0.035 | 0.081 |
| IgG1 | 673 (557–815) | 608.5 (493.5–767.5) | 541 (401–766) | 623 (504–772) | 0.009 | 0.005 |
| IgG2 | 339 (239–506) | 318 (209–430.5) | 270.5 (162–369) | 323.5 (221–447) | <0.001 | <0.001 |
| IgG3 | 60.8 (43.1–80) | 61.3 (43.5–85.4) | 43.1 (29–70) | 61.3 (43.4–83.3) | <0.001 | <0.001 |
| IgG4 | 46.8 (27.7–103) | 43.3 (18.6–74.5) | 28.5 (15–58) | 44.7 (21.4–80.9) | 0.001 | 0.001 |
| IgA | 233 (160–342) | 254 (186–333) | 221.5 (132–310) | 249 (184–340) | 0.018 | 0.008 |
| IgM | 107 (58–162) | 76.5 (53–121) | 83 (58–117) | 81 (54–129) | 0.032 | 0.705 |
Data as median and IQR (25–75th centile) in parentheses.
CAP, community-acquired pneumonia; ICU, intensive care unit.