Table 2

Results of rebiopsy and association between diagnostic yield and factors

Tissue obtained
Patient characteristicsSuccessFailurep Value
Age
 <7051130.81
 ≥70378
Sex
 Male4280.47
 Female4613
Smoking status
 Never45140.23
 Former/current437
Histology
 Adenocarcinoma82190.65
 Squamous cell carcinoma62
Mutational status
 EGFR/ALK53140.63
 Wild357
Tumour size
 <30 mm2915<0.01
 ≥30 mm596
Rebiopsy site
 Primary80191.00
 Metastatic82
Previous treatment
 Platinum-based
  Received63140.79
  Not received257
 Antiangiogenesis agent
  Received2980.80
  Not received5913
 Molecular targeting agent
  Received48140.34
  Not received407
Response of last treatment
 CR/PR50100.47
 SD/PD3811
  • ALK, anaplastic lymphoma kinase; CR, complete response; EGFR, epidermal growth factor receptor; PD, progressive disease; PR, partial response; SD, stable disease.