Table 2

Results of rebiopsy and association between diagnostic yield and factors

	Tissue obtained
Patient characteristics	Success	Failure	p Value
Age
<70	51	13	0.81
≥70	37	8
Sex
Male	42	8	0.47
Female	46	13
Smoking status
Never	45	14	0.23
Former/current	43	7
Histology
Adenocarcinoma	82	19	0.65
Squamous cell carcinoma	6	2
Mutational status
EGFR/ALK	53	14	0.63
Wild	35	7
Tumour size
<30 mm	29	15	<0.01
≥30 mm	59	6
Rebiopsy site
Primary	80	19	1.00
Metastatic	8	2
Previous treatment
Platinum-based
Received	63	14	0.79
Not received	25	7
Antiangiogenesis agent
Received	29	8	0.80
Not received	59	13
Molecular targeting agent
Received	48	14	0.34
Not received	40	7
Response of last treatment
CR/PR	50	10	0.47
SD/PD	38	11

ALK, anaplastic lymphoma kinase; CR, complete response; EGFR, epidermal growth factor receptor; PD, progressive disease; PR, partial response; SD, stable disease.