All (n=4857) | PREO-POSTO (n=1889) | PREN-POSTN (n=2421) | PREO-POSTN (n=379) | PREN-POSTO (n=168) | P value* | |
Change in FEV1, mL±SD | −198.1±294.5 | −202.5±320.2 | −198.8±268.5 | −203.6±282.2 | −125.6±365.5 | <0.001 |
Change in MMRC ±SD | 0.06±1.24 | 0.19±1.26 | −0.04±1.22 | 0.03±1.08 | 0.05±1.36 | 0.42 |
Change in SGRQ ±SD | 0.15±15.3 | 1.5±15.2 | −0.8±15.4 | −0.88±14.6 | 0.98±16 | 0.86 |
Change in 6-MWD, feet±SD | −130.9±360.6 | −172.7±366.4 | −103.7±357 | −103±327.4 | −123.5±377 | <0.001 |
*Comparison between PREO-POSTN and PREN-POSTO using χ2 and Student’s t-test or Wilcoxon rank sum test.
6-6-MWD = 6-min walk distance; MMRC, modified Medical Research Council dyspnoea score; SGRQ, St. George’s Respiratory Questionnaire score.
PREN-POSTN: prebronchodilator FEV1/FVC >0.7 and postbronchodilator FEV1/FVC >0.7.
PREO-POSTNO: prebronchodilator FEV1/FVC <0.7 and postbronchodilator FEV1/FVC <0.7.
PREO-POSTN: prebronchodilator FEV1/FVC <0.7 and postbronchodilator FEV1/FVC >0.7.
PREN-POSTO: prebronchodilator FEV1/FVC >0.7 and postbronchodilator FEV1/FVC <0.7.