Changes in questionnaire scores over time
| Score | Baseline (n=185) | 6 months (n=153) | 12 months (n=140) | 18 months (n=126) | P value |
| emPHasis-10 | 27.0 (12.0) | 25.8 (11.6) | 25.4 (11.8) | 25.4 (12.3) | 0.54 |
| Dyspnoea-12 | 11.5 (9.4) | 10.5 (9.2) | 10.3 (8.8) | 10.8 (9.2) | 0.20 |
| FSS | 5.1 (1.6) | 4.8 (1.6) | 4.8 (1.6) | 4.7 (1.7) | 0.07 |
| MOS-Sleep Index | 39.4 (19.2) | 38.8 (20.0) | 37.7 (19.0) | 39.4 (19.7) | 0.48 |
| HADS-Anxiety | 7.1 (4.7) | 6.3 (4.4) | 6.3 (4.3) | 6.6 (4.5) | 0.04 |
| HADS-Depression | 6.0 (3.8) | 5.4 (3.8) | 5.2 (3.5) | 5.3 (3.6) | 0.39 |
Multilevel regression methods were used to examine changes in the various scores among the four time points. Figures reported are the mean (SD) score at each time point.
FSS, Fatigue Severity Scale; HADS, Hospital Anxiety and Depression Scale; MOS, Medical Outcomes Study.