Table 5

Association between individual predictor factors and emPHasis-10 scores (n=126)

VariableCategory/termUnadjustedAdjusted*
Coefficient (95% CI)P valueCoefficient (95% CI)P value
Dyspnoea-12†Linear term6.5 (5.4 to 7.6)<0.0016.7 (5.6 to 7.9)<0.001
Squared term−0.4 (−0.6 to 0.2)−0.4 (−0.6 to 0.2)
MOS-Sleep Index‡1.7 (1.2 to 2.2)<0.0011.7 (1.2 to 2.2)<0.001
FSS†3.2 (2.8 to 3.7)<0.0013.3 (2.8 to 3.7)<0.001
HADS-Anxiety1.1 (0.9 to 1.3)<0.0011.1 (0.9 to 1.3)<0.001
HADS-DepressionLinear term2.2 (1.6 to 2.7)<0.0012.2 (1.7 to 2.8)<0.001
Squared term−0.06 (−0.09 to 0.02)−0.06 (−0.09 to 0.02)
WHO FC (patient reported)FC I/II0<0.0010<0.001
FC III5.1 (3.7 to 6.6)5.3 (3.8 to 6.7)
FC IV7.5 (5.4 to 9.5)7.5 (5.4 to 9.6)
  • *Adjusted for diagnosis, age and gender.

  • †Regression coefficients reported for a 5-unit increase in predictor variable.

  • ‡Regression coefficients reported for a 10-unit increase in predictor variable.

  • FSS, Fatigue Severity Scale; HADS, Hospital Anxiety and Depression Scale; MOS, Medical Outcomes Study; WHO FC, WHO functional class.