Variable | Category/term | Unadjusted | Adjusted* | ||
Coefficient (95% CI) | P value | Coefficient (95% CI) | P value | ||
Dyspnoea-12† | Linear term | 6.5 (5.4 to 7.6) | <0.001 | 6.7 (5.6 to 7.9) | <0.001 |
Squared term | −0.4 (−0.6 to 0.2) | −0.4 (−0.6 to 0.2) | |||
MOS-Sleep Index‡ | – | 1.7 (1.2 to 2.2) | <0.001 | 1.7 (1.2 to 2.2) | <0.001 |
FSS† | – | 3.2 (2.8 to 3.7) | <0.001 | 3.3 (2.8 to 3.7) | <0.001 |
HADS-Anxiety | – | 1.1 (0.9 to 1.3) | <0.001 | 1.1 (0.9 to 1.3) | <0.001 |
HADS-Depression | Linear term | 2.2 (1.6 to 2.7) | <0.001 | 2.2 (1.7 to 2.8) | <0.001 |
Squared term | −0.06 (−0.09 to 0.02) | −0.06 (−0.09 to 0.02) | |||
WHO FC (patient reported) | FC I/II | 0 | <0.001 | 0 | <0.001 |
FC III | 5.1 (3.7 to 6.6) | 5.3 (3.8 to 6.7) | |||
FC IV | 7.5 (5.4 to 9.5) | 7.5 (5.4 to 9.6) |
*Adjusted for diagnosis, age and gender.
†Regression coefficients reported for a 5-unit increase in predictor variable.
‡Regression coefficients reported for a 10-unit increase in predictor variable.
FSS, Fatigue Severity Scale; HADS, Hospital Anxiety and Depression Scale; MOS, Medical Outcomes Study; WHO FC, WHO functional class.