Deposition of particles in the human respiratory tract in the size range 0.005–15 μm

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Abstract

Experimentally determined total and regional deposition data are presented for breathing monodisperse aerosols of a wide particle size range at different patterns through the mouth and nose. From these data simple analytical expressions were derived for the efficiencies of the nasal passages, larynx, upper and lower ciliated thoracic airways and the nonciliated portion of the lungs in collecting particles from inspired aerosols. Thus, empirical expressions are now available for the calculation of total and regional deposition in the human respiratory tract for particles of any size and density inspired at any pattern through the mouth or nose.

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