Original article: general thoracicAssessment of outcomes in typical and atypical carcinoids according to latest WHO classification
Section snippets
Patients and methods
From 1980 to 2001, 98 patients underwent parenchyma lung resection for carcinoid tumors in our Thoracic Department of the University of Milan. There were 52 men and 46 women. The original histologic diagnosis has been reclassified according to the 1999 W.H.O. classification by a spectrum of pathologists from different departments. Therefore, using actual criteria, there were 88 cases of typical carcinoid and 10 cases of atypical carcinoid.
We used contrast-enhanced computed tomography (CT) for
Results
We did not have any intraoperative deaths. The 90-day mortality rate was 2% of patients: one myocardial infarction and one stroke. We never had severe postoperative surgical complications; we noted four cardiac arrhythmias and five pneumonias pharmacologically recovered.
At the time of last follow-up in 2001, information for typical carcinoid group was noted as follows: 6 (6.8%) of the 88 patients died from recurrence of disease. Five were N1 (31.2% of all N1 in typical carcinoid subtype) and 1
Comment
Carcinoids represent a spectrum of neuroendocrine malignant tumors with different behaviors and prognoses depending on their differentiation. The 1999 W.H.O. by Travis and associates recognized two different forms of carcinoid: typical carcinoid and atypical carcinoid.
Because, unfortunately, most reports regarding prognosis and management of these tumors have been published before the 1999 W.H.O. one, currently, the appropriate standard surgical management of typical and atypical carcinoids is
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2019, Lung CancerCitation Excerpt :Completing surgery for residual or recurrence of disease was common practice in all selected studies. Studies related to surgical treatment were predominantly retrospective cohort studies [3,13,16–41] and performed in Europe [3,13,17–19,21–29,31,36,38,40–50]. Both anatomical pulmonary resections (lobectomy, bilobectomy and pneumonectomy) and parenchyma sparing surgical techniques (segmentectomy, sleeve lobectomy, bronchial sleeve, wedge or enucleation of the tumor) were described.
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