Case reportAn Unusual Case of Aspergillus Fibrosing Mediastinitis
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Comment
Aspergillus, a mold found throughout the environment, may cause invasive disease in the immunocompromised host, but it is a rare pathogen in the immunocompetent individual [1, 2, 3]. The most common manifestation of invasive aspergillosis is pneumonia, because the lungs serve as the main portal of entry for inhaled spores [4]. Although there are many causes of fibrosing mediastinitis, most cases are usually due to the immunologic reaction to the antigens of Histoplasma, also found throughout
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Cited by (14)
Aspergillus mediastinitis following post-immunotherapy lobectomy for oligometastatic lung
2022, Revue des Maladies RespiratoiresIdiopathic fibrosing mediastinitis: Spectrum of imaging findings with emphasis on its association with IgG4-related disease
2015, Clinical ImagingCitation Excerpt :The majority of granulomatous FM cases in the United States are associated with histoplasmosis infection and are characterized by an idiosyncratic proliferation of fibrous tissue in response to antigenic stimulation in regions where the soil-based fungus Histoplasma capsulatum is endemic [6]. However, other infections, such as tuberculosis, blastomycosis, aspergillosis, and cryptococcosis, can also cause granulomatous FM, as can sarcoidosis [7–11]. Nongranulomatous FM is considered an idiopathic immune-mediated reaction to different autoimmune syndromes, radiation therapy, or drugs (e.g., methysergide) [12–16].
Fibrosing mediastinitis due to Aspergillus with dominant cardiac involvement: Report of two autopsy cases with review of literature
2014, Cardiovascular PathologyCitation Excerpt :The antemortem diagnosis of fibrosing mediastinitis is often challenging on imaging, as it could mimic any other mediastinal mass. The diagnosis can be established by a tissue biopsy or a culture study [3]. Serum galactomannan and fungal serology can also give a clue towards etiological diagnosis.
Chronic granulomatous 'Aspergillus lung mass'
2020, Monaldi Archives for Chest DiseaseFungal fibrosing mediastinitis in pregnancy - Case report with review of literature
2019, Journal of Postgraduate Medicine