Prostate cancer is the most prevalent cancer in males in Western countries. The reported
incidence in Asia is much lower than that in African Americans and European Caucasians …

The metabolic syndrome is a highly complex breakdown of normal physiology characterized
by obesity, insulin resistance, hyperlipidemia, and hypertension. Type 2 diabetes is a major …

To increase understanding of the epidemiology, risks, consequences and resource
utilization of Clostridium difficile infection (CDI) in Japan, a systematic literature review was …

Desmosomes in tissues are resistant to disruption by chelation of extracellular calcium. It
has been suggested that this represents a hyper-adhesive state of these intercellular …

As little is known about antimicrobial resistance genes in fish farms, this study was
conducted to monitor the incidence and prevalence of a wide range of antimicrobial …

Background: Chronic pulmonary disorders, such as chronic obstructive pulmonary disease
(COPD) and fibrosing lung diseases, and atrial fibrillation (AF), are prevalent in elderly …

Aims Inhibition of vascular smooth muscle cell (VSMC) proliferation by intracellular cAMP
prevents excessive neointima formation and hence angioplasty restenosis and vein-graft …

Rationale: Mitogen-activated protein kinase (MAPK) pathways provide a critical connection
between extrinsic and intrinsic signals to cardiac hypertrophy. Extracellular signal-regulated …

Mitogen-activated protein kinase kinase (MKK) 4 is a critical member of the mitogen-
activated protein kinase family. It is able to activate the c-Jun NH2-terminal protein kinase …

Imidapril is an angiotensin-converting enzyme inhibitor that is widely used in treating
hypertension, although the responses vary among individuals. We investigated whether a …