[HTML][HTML] MicroRNAs in extracellular vesicles: potential cancer biomarkers
T Kinoshita, KW Yip, T Spence, FF Liu - Journal of human genetics, 2017 - nature.com
Extracellular vesicles (EV) are small membrane-bound structures that are secreted by
various cell types, including tumor cells. Recent studies have shown that EVs are important …
various cell types, including tumor cells. Recent studies have shown that EVs are important …
Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation …
A Murakami, D Takahashi, T Kinoshita… - …, 2002 - academic.oup.com
Zerumbone (ZER), a sesquiterpene from the edible plant Zingiber zerumbet Smith, has
recently been found to suppress tumor promoter 12-O-tetradecanoylphorbol-13-acetate …
recently been found to suppress tumor promoter 12-O-tetradecanoylphorbol-13-acetate …
MicroRNAs function as tumor suppressors or oncogenes: aberrant expression of microRNAs in head and neck squamous cell carcinoma
N Nohata, T Hanazawa, T Kinoshita, Y Okamoto… - Auris Nasus …, 2013 - Elsevier
MicroRNAs (miRNAs) are endogenous short non-coding RNA molecules that regulate gene
expression by repressing translation or cleaving RNA transcripts in a sequence-specific …
expression by repressing translation or cleaving RNA transcripts in a sequence-specific …
[HTML][HTML] Genistein inhibits prostate cancer cell growth by targeting miR-34a and oncogenic HOTAIR
T Chiyomaru, S Yamamura, S Fukuhara, H Yoshino… - PloS one, 2013 - journals.plos.org
Objective Genistein is a soy isoflavone that has antitumor activity both in vitro and in vivo. It
has been shown that genistein inhibits many type of cancers including prostate cancer …
has been shown that genistein inhibits many type of cancers including prostate cancer …
[HTML][HTML] Significance of programmed cell death-ligand 1 expression and its association with survival in patients with small cell lung cancer
H Ishii, K Azuma, A Kawahara, K Yamada… - Journal of thoracic …, 2015 - Elsevier
Background Programmed cell death 1 receptor–ligand interaction is a major pathway often
hijacked by tumors to suppress immune control. The aim of this retrospective study was to …
hijacked by tumors to suppress immune control. The aim of this retrospective study was to …
[HTML][HTML] Predictive relevance of PD-L1 expression combined with CD8+ TIL density in stage III non-small cell lung cancer patients receiving concurrent …
T Tokito, K Azuma, A Kawahara, H Ishii… - European journal of …, 2016 - Elsevier
Background Expression of programmed cell death-ligand 1 (PD-L1) is known to be a
mechanism whereby cancer can escape immune surveillance, but little is known about …
mechanism whereby cancer can escape immune surveillance, but little is known about …
[HTML][HTML] The MicroRNA Expression Signature of Bladder Cancer by Deep Sequencing: The Functional Significance of the miR-195/497 Cluster
T Itesako, N Seki, H Yoshino, T Chiyomaru… - PloS one, 2014 - journals.plos.org
Current genome-wide microRNA (miRNA) expression signature analysis using deep
sequencing technologies can drive the discovery of novel cancer pathways regulated by …
sequencing technologies can drive the discovery of novel cancer pathways regulated by …
[HTML][HTML] Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion by targeting focal adhesion pathways in cervical squamous cell carcinoma
N Yamamoto, T Kinoshita… - International …, 2013 - spandidos-publications.com
Cervical cancer is one of the most common cancers in women. More than 275,100 women
die from cervical cancer each year. Cervical squamous cell carcinoma (cervical SCC), one …
die from cervical cancer each year. Cervical squamous cell carcinoma (cervical SCC), one …
[HTML][HTML] Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma
Y Moriya, N Nohata, T Kinoshita, M Mutallip… - Journal of human …, 2012 - nature.com
Abstract Analysis of the microRNA (miRNA) expression signature of lung squamous cell
carcinoma (lung-SCC) revealed that the expression levels of miR-133a were significantly …
carcinoma (lung-SCC) revealed that the expression levels of miR-133a were significantly …
[HTML][HTML] Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma
T Kinoshita, T Hanazawa, N Nohata, N Kikkawa… - Oncotarget, 2012 - ncbi.nlm.nih.gov
Recent our microRNA (miRNA) expression signature revealed that expression of microRNA-
218 (miR-218) was reduced in cancer tissues, suggesting a candidate of tumor suppressor …
218 (miR-218) was reduced in cancer tissues, suggesting a candidate of tumor suppressor …