Inert gas washout tests, performed using the single- or multiple-breath washout technique,
were first described over 60 years ago. As measures of ventilation distribution inhomogeneity, …

Air pollution exposure has increased extensively in recent years and there is considerable
evidence that exposure to particulate matter can lead to adverse respiratory outcomes. The …

OBJECTIVE: Neonatal sepsis causes high mortality and morbidity in preterm infants, but less
is known regarding the long-term outcome after sepsis. This study aimed to determine the …

There is increasing evidence of the adverse impact of prenatal exposure to air pollution.
This is of particular interest, as exposure during pregnancy—a crucial time span of important …

The lung clearance index (LCI) is a lung function parameter derived from the multiple-breath
washout (MBW) test. Although first developed 60 years ago, the technique was not widely …

The diagnosis of primary ciliary dyskinesia is often confirmed with standard, albeit complex
and expensive, tests. In many cases, however, the diagnosis remains difficult despite the …

Interleukin-8 (IL-8) activates neutrophils via the chemokine receptors CXCR1 and CXCR2.
However, the airways of individuals with cystic fibrosis are frequently colonized by bacterial …

The airways of cystic fibrosis (CF) patients are characterised by neutrophils that release
high amounts of elastase overwhelming the local antiprotease shield. Inhalation of α 1 -…

Post-natal exposure to air pollution is associated with diminished lung growth during school
age. The current authors aimed to determine whether pre-natal exposure to air pollution is …

Background: Acute respiratory infections (ARI) are a major cause of morbidity in infancy
worldwide, with cough and wheeze being alarming symptoms to parents. We aimed to analyze …