The prevalence of quadriceps weakness in COPD and the relationship with disease severity

…, NS Hopkinson, SA Natanek, WDC Man… - European …, 2010 - Eur Respiratory Soc
Quadriceps strength relates to exercise capacity and prognosis in chronic obstructive
pulmonary disease (COPD). We wanted to quantify the prevalence of quadriceps weakness in …

Magnetic stimulation for the measurement of respiratory and skeletal muscle function

WDC Man, J Moxham, MI Polkey - European respiratory …, 2004 - Eur Respiratory Soc
Respiratory and skeletal muscle function is of interest in many areas of pulmonary and
critical care medicine. The capacity of the respiratory muscle pump to respond to the load …

Acute effect of oral steroids on muscle function in chronic obstructive pulmonary disease

NS Hopkinson, WDC Man, MJ Dayer… - European …, 2004 - Eur Respiratory Soc
Prospective data to support the hypothesis that corticosteroids are a significant cause of
muscle weakness in patients with chronic obstructive pulmonary disease (COPD) are lacking. …

[HTML][HTML] Klotho and smoking–an interplay influencing the skeletal muscle function deficits that occur in COPD

…, PLB Bruijnzeel, N Hart, NS Hopkinson, WDC Man… - Respiratory …, 2016 - Elsevier
Background Klotho is an ‘anti-ageing’ hormone and transmembrane protein; Klotho deficient
mice develop a similar ageing phenotype to smokers including emphysema and muscle …

Postprandial effects on twitch transdiaphragmatic pressure

WDC Man, YM Luo, N Mustfa… - European …, 2002 - Eur Respiratory Soc
Twitch transdiaphragmatic pressure (P di,tw ), measured following magnetic stimulation of
the phrenic nerves, is used to assess diaphragm strength, contractility and fatigue. Although …

The Six-Minute Step Test as an Exercise Outcome in COPD

…, M Maddocks, NS Hopkinson, CM Nolan, WDC Man - 2022 - bura.brunel.ac.uk
Methods Participants were prospectively recruited from those attending PR assessment
clinics. Inclusion criteria were: a diagnosis of COPD, Medical Research Council (MRC) …

S109 Five-Repetition Sit-To-Stand Test: Reliability, Validity and Response to Pulmonary Rehabilitation in COPD

…, D Dilaver, M Peasey, MGS Ng, MI Polkey, WDC Man - Thorax, 2012 - thorax.bmj.com
Background Validated field exercise tests, such as the six minute walk test and incremental/endurance
shuttle walks, require space and may be time-consuming as repeat walks are …

P47 Patient characteristics of those referred and not referred for early post-hospitalisation pulmonary rehabilitation

…, AM Nolan, S Fleming, M Haselden, WDC Man - Thorax, 2013 - thorax.bmj.com
Background Early post-hospitalisation pulmonary rehabilitation (PR) following acute
exacerbation of COPD (AECOPD) has been shown to improve health-related quality of life (HRQOL)…

P102 Post-Hospitalisation Outpatient Pulmonary Rehabilitation: A Translational Gap?

…, C Howe, BM Haselden, S Fleming, WDC Man - Thorax, 2012 - thorax.bmj.com
Background Recent trials and meta-analyses of early post-hospitalisation pulmonary
rehabilitation (PR) in COPD have demonstrated improvements in exercise capacity, health-related …

P238 Minimal clinically important difference for pedometer step count in COPD: a prospective analysis

…, S Patel, JA Walsh, RE Barker, SF Clarke, WDC Man… - Thorax, 2021 - thorax.bmj.com
Background Infection control precautions arising from the COVID-19 pandemic has led to
challenges undertaking face-to-face exercise testing required for pulmonary rehabilitation (PR) …