Baseline characteristics of 795 individuals with COPD
| Statins N=253 | No statins N=542 | p Value | |
|---|---|---|---|
| Mean age at enrolment in years (SD) | 68.2 (8.4) | 67.6 (10.5) | 0.391 |
| Male (number (%)) | 169 (66.8) | 317 (58.5) | 0.025 |
| Current smoker (number (%)) | 59 (23.3) | 153 (28.2) | 0.145 |
| Mean BMI at enrolment (SD) | 28.5 (5.7) | 26.5 (5.2) | 0.000 |
| GOLD stage (number (%)) | 0.024 | ||
| I | 28 (11.1) | 42 (7.8) | |
| II | 114 (45.2) | 209 (38.8) | |
| III | 93 (36.9) | 223 (41.4) | |
| IV | 17 (6.7) | 65 (12.1) | |
| Lung function | |||
| Mean FEV1 in litres (SD) | 1.5 (0.6) | 1.4 (0.6) | 0.007 |
| Mean FEV1% predicted (SD) | 54.6 (18.7) | 50.9 (19.6) | 0.012 |
| Mean FEV1/VC % predicted (SD) | 46.9 (13.7) | 43.4 (13.4) | 0.001 |
| Comorbidities (number (%)) | |||
| Congestive heart failure | 63 (24.9) | 76 (14.0) | 0.000 |
| Myocardial infarction | 272 (8.7) | 8 (1.5) | 0.000 |
| Hypertension | 19 (7.5) | 21 (3,9) | 0.029 |
| Diabetes mellitus | 37 (14.6) | 15 (2.8) | 0.000 |
| Mean mMRC score (SD) | 1.8 (1.2) | 1.7 (1.3) | 0.500 |
| Mean ADO score (SD) | 4.2 (1.6) | 4.1 (2.0) | 0.745 |
| Mean BOD score (SD) | 2.3 (1.6) | 2.5 (1.8) | 0.061 |
| Median pack-years | 35.4 | 35.0 | 0.920 |
AECOPD, acute exacerbation of COPD; COPD, chronic obstructive pulmonary disease; FEV, forced expiratory volume; mMRC, modified Medical Research Council Dyspnea Questionnaire; VC, vital capacity.