Unadjusted inverse oxygenation indices and PF ratio*
| OI mean (95% CI) | PF mean (95% CI) | |
|---|---|---|
| Baseline | ||
| Pulmonary perfusion with oxygenated blood | 1.15 (0.78 to 1.52) 0.89 | 392.35 (348.06 to 436.64) |
| Pulmonary perfusion with HTK solution | (0.74 to 1.04) | 350.14 (314.80 to 385.48) |
| No pulmonary perfusion | 0.97 (0.83 to 1.11) | 413.43 (371.37 to 455.49) |
| 1 hour after CPB start | ||
| Pulmonary perfusion with oxygenated blood | 0.60 (0.48 to 0.73) | 272.00 (225.90 to 318.09) |
| Pulmonary perfusion with HTK solution | 0.46 (0.32 to 0.59) | 199.96 (160.15 to 239.77) |
| No pulmonary perfusion | 0.69 (0.55 to 0.83) | 293.02 (245.93 to 340.12) |
| 3 hours after CPB start | ||
| Pulmonary perfusion with oxygenated blood | 0.41 (0.33 to 0.48) | 282.11 (237.46 to 326.76) |
| Pulmonary perfusion with HTK solution | 0.36 (0.30 to 0.42) | 249.64 (214.58 to 284.70) |
| No pulmonary perfusion | 0.52 (0.27 to 0.77) | 267.84 (216.66 to 319.03) |
| 5 hours after CPB start | ||
| Pulmonary perfusion with oxygenated blood | 0.65 (0.37 to 0.94) | 337.15 (260.56 to 413.74) |
| Pulmonary perfusion with HTK solution | 1.12 (0.55 to 1.69) | 262.86 (235.55 to 290.18) |
| No pulmonary perfusion | 1.52 (0.67 to 2.37) | 285.84 (238.32 to 333.36) |
| 7 hours after CPB start | ||
| Pulmonary perfusion with oxygenated blood | 1.99 (1.20 to 2.77) | 321.00 (286.47 to 355.54) |
| Pulmonary perfusion with HTK solution | 2.14 (1.46 to 2.82) | 274.82 (250.64 to 299.11) |
| No pulmonary perfusion | 1.99 (1.23 to 2.76) | 277.43 (239.55 to 315.32) |
| 21 hours after CPB start | ||
| Pulmonary perfusion with oxygenated blood | 4.48 (3.86 to 5.10) | 331.04 (285.54 to 376.54) |
| Pulmonary perfusion with HTK solution | 3.45 (3.06 to 3.84) | 266.03 (238.91 to 293.15) |
| No pulmonary perfusion | 3.58 (2.93 to 4.22) | 291.37 (254.58 to 328.16) |
*Intention-to-treat population.
CPB, cardiopulmonary bypass; HTK, histidine-tryptophan-ketoglutarate; OI, oxygenation index; PF, PaO2/FiO2 ratio in mm Hg.