Baseline patient characteristics and eosinophil counts during the study
| Baseline characteristics | Non-ICS arms (n=59) | ICS arms (n=53) |
|---|---|---|
| Age, years | 66 (61 to 71) | 64 (54 to 71) |
| Male, % | 80 | 74 |
| Smoking history, pack-years | 46 (33 to 55) | 42 (26 to 60) |
| Current smoker, % | 51 | 55 |
| Post-bronchodilator FEV1, L | 1.40 (1.07 to 1.65) | 1.50 (1.15 to 1.87) |
| Post-bronchodilator FEV1 per cent predicted | 50 (40 to 61) | 55 (45 to 63) |
| Eosinophil counts, cells/μL | Non-ICS arms (n=59) | ICS arms (n=53) |
| Eosinophil count at baseline | 230 (120 to 410) | 200 (120 to 310) |
| Change, week 6 | −20 (−80 to 70) | −30 (−90 to 10) |
| Change, week 12 | 10 (−80 to 80) | −30 (−90 to 20) |
| Percentage of patients with eosinophil count at baseline ≥150 | 71 | 66 |
| Percentage of patients with eosinophil count at baseline ≥300 | 34 | 26 |
Values presented as median (IQR) unless otherwise noted.
FEV1, forced expiratory volume in 1s; ICS, inhaled corticosteroids; IQR, interquartile range.