Table 2

Non-chemical triggers and risk of COPD exacerbation

Variable typeVariable descriptionOR95% CI−2log likelihood
SeasonSeason, ref=summer 417
Summer1.001.001.0
Spring2.591.554.35
Winter2.381.374.11
Fall6.643.8311.5
WeatherSpent time in cold air/cold weather in past week* 1.160.781.70468
Spent time in hot air/hot weather in past week* 0.500.340.75457
Local temperature (categorical) 422
 Cold (<40°F)1.01.01.0
 Moderate (40–50°F)2.501.514.12
 Warm (>50°F)0.550.360.84
Acute illnessRespiratory infection/cold in past week* 8.144.6714.2396
Physical activityTotal hours spent outside of the home*,§ 0.990.991.00469
Exercised in past week* 0.600.390.93462
  • *Based on self-reports from exposure questionnaires.

  • †Based on 7-day averages using data from NOAA collected at Worcester Regional Airport.

  • ‡Categorical representation of variable based on cut-offs identified in restricted cubic splines.

  • §Estimated as the sum of total ‘hours reported outdoors’, ‘hours reported in a vehicle’ and ‘hours reported indoors but not at home’.

  • COPD, chronic obstructive pulmonary disease.