Table 1

Key eligibility criteria for participation in INMARK®

Key inclusion criteria	Key exclusion criteria
Age ≥40 years	ALT or AST or total bilirubin >1.5 × upper limit of normal at screening
Diagnosis of IPF according to ATS/ERS/JRS/ALAT guidelines (Raghu et al, 20111 within last 3 years)	FEV₁/FVC<0.70 (prebronchodilator)
Chest HRCT (performed within 18 months of screening) and surgical lung biopsy pattern (if available) consistent with a diagnosis of IPF, assessed by central review	Myocardial infarction within 6 months or unstable angina within 1 month of screening
FVC ≥80% predicted at screening	Bleeding risk (eg, requiring full-dose therapeutic anticoagulation or high-dose antiplatelet therapy)
	History of a thrombotic event within 12 months of screening
	Treatment with nintedanib, pirfenidone, azathioprine, cyclophosphamide, cyclosporine or any investigational drug was not permitted within 4 weeks of randomisation

ALT, alanine transaminase; AST, aspartate transaminase; FEV₁, forced expiratory volume in 1 s; FVC, forced vital capacity; HRCT, high-resolution CT; IPF, idiopathic pulmonary fibrosis.