Table 1

Demographic and clinical variables

VariablesPE with fever (n=59)PE without fever
(n=182)
Total (n=241)P values
Age52.518 (15.457)58.678 (16.452)57.170 (16.399)0.01
Gender (Female)27 (45.8%)94 (51.6%)121 (50.2%)0.52
Comorbidities
 CHF1 (1.7%)23 (12.6%)24 (10.0%)0.02
 Malignancy8 (13.6%)32 (17.6%)40 (16.6%)0.60
 OAD13 (22.0%)34 (18.7%)47 (19.5%)0.70
 History of smoking26 (44.1%)38 (20.9%)64 (26.6%)<0.001
Vital signs
 Tmax in 1 week of PE (°F) (±SD)101.576 (±0.911)98.719 (±0.801)99.419 (1.483)<0.001
 Heart rate (beats/min) (±SD)101.136 (±24.449)90.199 (±20.138)92.888 (21.743)<0.001
 MAP (mm Hg) (±SD)84.879 (±16.965)88.456 (±16.572)87.592 (16.703)0.15
 Systolic BP (mm Hg) (±SD)115.932 (±24.143)123.720 (±19.685)121.813 (21.080)0.01
 Oxygen saturation (%)(SD)95.724 (±5.742)96.808 (±3.900)96.535 (4.448)0.10
PE relevant data
 Simple PE26 (44.1%)115 (63.2%)141 (58.5%)0.01
 Massive and submassive PE33 (55.9%)67 (36.8%)100 (41.5%)0.01
 Use of TPA4 (6.8%)2 (1.1%)6 (2.5%)0.05
 Use of anticoagulation57 (96.6%)164 (90.1%)221 (91.7%)0.19
 Laterality (Bilateral)30 (50.8%)76 (41.8%)106 (44.0%)0.28
 Pulmonary infarct5 (8.5%)4 (2.2%)9 (3.7%)0.07
 DVT15/45 (33.3%)23/132 (17.4%)38/177 (21.5%)0.03
 RVSP n (±SD)42.370 (±13.920)39.411 (±13.586)40.079 (13.682)0.20
Infection data
 Leucocyte count k/ul (±SD)10.976 (5.848)8.797 (5.013)9.330 (5.301)0.006
 Positive blood culture within 1 week of PE1 (1.9%)1 (0.7%)2 (1.0%)1.000
 Urine culture positive within 1 week of PE3 (6.2%)9 (7.3%)12 (7.0%)1.000
 Antibiotics given within 1 week of PE37 (62.7%)49 (26.9%)86 (35.7%)<0.001
  • BP, blood pressure; CHF, congestive heart failure; DVT, deep venous thrombosis; MAP, mean arterial pressure; OAD, obstructive airway disease; PE, pulmonary embolism;RVSP, right ventricular systolic pressure; TPA, tissue plasminogen activator; Tmax, maximum temperature.