Bilaterally summed composite scores for regional atrophy in the control and COPD groups (presented as mean±SD)
| Control subjects (n=25) | Patients with COPD (n=25) | P values | Corrected p values* | |
| Frontal | 5.08±2.68 | 7.32±3.26 | 0.01† | 0.02† |
| Temporal | 5.76±3.27 | 7.72±4.77 | 0.10 | 0.06 |
| Hippocampal | 4.60±1.89 | 5.24±3.06 | 0.38 | 0.05 |
*Generalised linear model multivariate analysis controlling for group differences in Charlson Comorbidity Index, pack-years and Hospital Anxiety and Depression (HAD) scores.
†Statistically significant result.
COPD, chronic obstructive pulmonary disease.