Patient characteristics | Pre-MDT group (n=26) | Post-MDT group (n=46) | P value |
Gender (% male) | 73.1 | 69.6 | 0.794 |
Age (years) | 69.0±1.8 | 72.3±1.8 | 0.197 |
Smoking history (number of patients) | 0.409 | ||
Current | 0 | 1 | |
Ex-smoker | 13 | 29 | |
Never | 12 | 14 | |
Unknown | 1 | 2 | |
FVC (% predicted) | 59.2±2.4, n=25 | 58.6±2.3, n=45 | 0.856 |
TLCO (% predicted) | 28.3±2.2, n=16 | 32.9±2.1, n=27 | 0.140 |
6MWT distance (m) | 184.2±20.6, n=23 | 186.5±13.8, n=43 | 0.927 |
Minimum saturation on 6MWT (%) | 80.8±1.7, n=23 | 82.98±1.0, n=43 | 0.294 |
Oxygen dependency (number of patients) | 0.415 | ||
LTOT | 15 | 32 | |
Ambulatory OT | 7 | 11 | |
None | 4 | 1 | |
Declined | 0 | 2 | |
NT-proBNP (pg/mL) | 1283±614.2, n=11 | 1223±305.9, n=38 | 0.931 |
ECHO suggestion of raised pulmonary pressures | 3(n=13) | 8 (n=34) | 0.999 |
Baseline demographics of pre-MDT (n=26) and post-MDT (n=46) cohorts were statistically comparable. Patients had moderately severe disease as determined by their lung function, with high dependency on oxygen and evidence of raised NT-proBNP. Data presented as mean±SEM unless otherwise stated.
Ambulatory OT, ambulatory oxygen therapy; ECHO, echocardiogram; FVC, Forced Vital Capacity; LTOT, long-term oxygen therapy; MDT, multidisciplinary team; 6MWT, 6-min walk test; NT-proBNP, N-terminal pro B-type natriuretic peptide; TLCO, gas transfer of the lung for carbon monoxide.