Mild disease severity | Moderate–severe | |
Severity Index scoring | Baseline | Baseline |
Body Mass Index | Annual | Annual |
Exacerbation history | Annual | 6 monthly |
Sputum culture | Annual | 6 monthly |
MRC Dyspnoea Score | Annual | 6 monthly |
Spirometry | Annual | Annual |
CT (radiological extent) | At diagnosis*‡ | At diagnosis*‡ |
Sputum mycobacterial culture† | Baseline‡ | Baseline‡ |
Oxygen saturation monitoring (SpO2) | Annual | 6 monthly |
Aetiological investigations | At diagnosis‡ | At diagnosis‡ |
Comorbidities assessment | At diagnosis‡ | At diagnosis‡ |
*Consider repeat CT scanning in patients with primary immunodeficiency with scan interval of 3-5-years.
†This may need tailored in light of the local prevalence rates of NTM infections and in some centres may need undertaken on a regular basis. Further cultures at exacerbationmay be appropriate.
‡Repeat investigations if a deteriorating patient.
MRC, Medical Research Council.