Table 1

PAVM cohort characteristics

MaleFemaleP value
Age50 (20–81)53 (20–85)0.37
MRC Dyspnoea Scale1 (1–5)2 (1–5)0.032
NYHA class1 (1–4)1 (1–4)0.13
VSAQ score10.5 (1–13)7 (1–12)0.0018
SaO2 (%)96 (89–98)96 (80–96)0.67
CaO2 (mL/L)189 (160–219)168 (87–194)0.0003
Haemoglobin (g/L)152 (123–197)132 (73–169)0.0004
Serum iron (μmol/L)14 (7–35)11 (1–48)0.020
Transferrin saturation index (%)22.5 (6–54)15 (1–66)0.016
Ferritin (μg/L)54 (11–306)26 (3–160)0.024
  • Selected demographics of the 71 patients with PAVMs. Data indicate median (minimum to maximum). P values were calculated by Mann-Whitney. Note that in this cohort, the MRC Dyspnoea Scale and NYHA class equivalents were assigned from the VSAQ score (see figure 3).

  • CaO2, arterial oxygen content; MRC, Medical Research Council; NYHA, New York Heart Association; PAVM, pulmonary arteriovenous malformation; SaO2, oxygen saturation; VSAQ, Veterans Specific Activity Questionnaire.