Table 2

Survival by HIV status and presence of a positive MRDT, signs of shock ±anaemia, MOF and malnutrition

Diagnostic categories (N)SurvivalVSPNA, no comorbidity*,
N=58
(% who survived or died; 95% CI)
Suspected TB,
N=20
(% who survived or died; 95% CI)
Signs of shock†; N=22
(% who survived or died; 95% CI)
MRDT positive; N=31
(% who survived or died; 95% CI)
Anaemia N=15
(% who survived or died; 95% CI)
MOF‡
>1 organ failure; N=54
(% who survived or died; 95% CI)
SAM (61% had MOF)
§
N=28
(% who survived or died; 95% CI)
HIV non-exp. or non-reactive (n=36)Survived19
(100%; 82% to 100%)
7
(78%; 40% to 97%)
3
(43%; 10% to 82%)
6
(60%; 26% to 88%)
2
(67%; 9% to 99%)
9
(56%; 30% to 80%)
4
(50%; 16% to 82%)
Died0
(0%; 0% to 17%)
2
(22%; 3% to 60%)
4
(57%; 18% to 90%)
4
(40%; 12% to 74%)
1
(33%; 1% to 91%)
7
(44%; 20% to 70%)
4
(50%; 16% to 82%)
HIV exposed or reactive (n=22)Survived8
(57%; 29% to 82%)
2
(22%; 3% to 60%)
1
(100%; 2.5% to 100%)
2
(50%; 7% to 93%)
1
(33%; 1% to 91%)
1
(14%; 0% to 58%)
2
(17%; 2% to 48%)
Died6
(43%; 18% to 71%)
7
(78%; 40% to 97%)
0
(0%, 0% to 97.5%)
2
(50%; 7% to 93%)
2
(67%; 9% to 99%)
6
(86%; 42% to 100%)
10
(83%; 52% to 98%)
HIV status unknown (n=59)Survived21
(91%; 72% to 99%)
1
(50%; 13% to 99%)
6
(43%; 18% to 71%)
12
(71%; 44% to 90%)
6
(67%; 30% to 93%)
15
(47%; 29% to 65%)
4
(50%; 16% to 82%)
Died2
(9%; 1% to 28%)
1
(50%; 13% to 99%)
8
(57%; 29% to 82%)
5
(29%; 10% to 56%)
3
(33%; 7% to 70%)
17
(53%; 35% to 71%)
4
(50%; 16% to 82%)
Total
(n=117)
Survived48
(86%; 74% to 94%)
10
(50%; 27% to 73%)
10
(45%; 24% to 68%)
20
(65%; 45% to 81%)
9
(60%; 32% to 84%)
25
(45%; 32% to 59%)
10
(36%; 19% to 56%)
Died8
(14%; 6% to 26%)
10
(50%; 27% to 73%)
12
(55%; 32% to 76%)
11
(35%; 19% to 55%)
6
(40%; 16% to 68%)
30
(55%; 41% to 68%)
18
(64%; 44% to 81%)
  • *For explanation of comorbidity and organ failure, see table 2. Please note that 5 of these 19 patients had ‘suspected TB’

  • †Signs of shock—all three positive signs: weak peripheral and/or central pulses, temperature gradient, delayed capillary refill time.28

  • ‡Organ failure, for example, respiratory failure, shock/impaired circulation, severe anaemia, coma/prolonged convulsion.

  • §Z-score weight/height<3; MUAC <115 mm; if not height/weight or MUAC available: weight/age z-score < −3.

  • ¶(61%) children with SAM had MOF.

  • MOF, multiorgan failure; MRDT, malaria rapid diagnostic tests; SAM, severeacute malnutrition; TB, tuberculosis; VSPNA, very severe pneumonia.