Table 2

Survival by HIV status and presence of a positive MRDT, signs of shock ±anaemia, MOF and malnutrition

Diagnostic categories (N)SurvivalVSPNA, no comorbidity*,
N=58
(% who survived or died; 95% CI)		Suspected TB,
N=20
(% who survived or died; 95% CI)		Signs of shock†; N=22
(% who survived or died; 95% CI)		MRDT positive; N=31
(% who survived or died; 95% CI)		Anaemia N=15
(% who survived or died; 95% CI)		MOF‡
>1 organ failure; N=54
(% who survived or died; 95% CI)		SAM (61% had MOF)
§
N=28
(% who survived or died; 95% CI)
HIV non-exp. or non-reactive (n=36)Survived19
(100%; 82% to 100%)		7
(78%; 40% to 97%)		3
(43%; 10% to 82%)		6
(60%; 26% to 88%)		2
(67%; 9% to 99%)		9
(56%; 30% to 80%)		4
(50%; 16% to 82%)
Died0
(0%; 0% to 17%)		2
(22%; 3% to 60%)		4
(57%; 18% to 90%)		4
(40%; 12% to 74%)		1
(33%; 1% to 91%)		7
(44%; 20% to 70%)		4
(50%; 16% to 82%)
HIV exposed or reactive (n=22)Survived8
(57%; 29% to 82%)		2
(22%; 3% to 60%)		1
(100%; 2.5% to 100%)		2
(50%; 7% to 93%)		1
(33%; 1% to 91%)		1
(14%; 0% to 58%)		2
(17%; 2% to 48%)
Died6
(43%; 18% to 71%)		7
(78%; 40% to 97%)		0
(0%, 0% to 97.5%)		2
(50%; 7% to 93%)		2
(67%; 9% to 99%)		6
(86%; 42% to 100%)		10
(83%; 52% to 98%)
HIV status unknown (n=59)Survived21
(91%; 72% to 99%)		1
(50%; 13% to 99%)		6
(43%; 18% to 71%)		12
(71%; 44% to 90%)		6
(67%; 30% to 93%)		15
(47%; 29% to 65%)		4
(50%; 16% to 82%)
Died2
(9%; 1% to 28%)		1
(50%; 13% to 99%)		8
(57%; 29% to 82%)		5
(29%; 10% to 56%)		3
(33%; 7% to 70%)		17
(53%; 35% to 71%)		4
(50%; 16% to 82%)
Total
(n=117)		Survived48
(86%; 74% to 94%)		10
(50%; 27% to 73%)		10
(45%; 24% to 68%)		20
(65%; 45% to 81%)		9
(60%; 32% to 84%)		25
(45%; 32% to 59%)		10
(36%; 19% to 56%)
Died8
(14%; 6% to 26%)		10
(50%; 27% to 73%)		12
(55%; 32% to 76%)		11
(35%; 19% to 55%)		6
(40%; 16% to 68%)		30
(55%; 41% to 68%)		18
(64%; 44% to 81%)

  • *For explanation of comorbidity and organ failure, see table 2. Please note that 5 of these 19 patients had ‘suspected TB’

  • †Signs of shock—all three positive signs: weak peripheral and/or central pulses, temperature gradient, delayed capillary refill time.28

  • ‡Organ failure, for example, respiratory failure, shock/impaired circulation, severe anaemia, coma/prolonged convulsion.

  • §Z-score weight/height<3; MUAC <115 mm; if not height/weight or MUAC available: weight/age z-score < −3.

  • ¶(61%) children with SAM had MOF.

  • MOF, multiorgan failure; MRDT, malaria rapid diagnostic tests; SAM, severeacute malnutrition; TB, tuberculosis; VSPNA, very severe pneumonia.