ECMO compared to standard care for ARDS
| Patient or population: adults with ARDS Settings: intensive care Intervention: ECMO Comparison: standard care | ||||||
| Outcomes | Illustrative comparative risks (95% CI) | Relative effect (95% CI) | No. of participants (studies) | Quality of evidence (GRADE) | Comments | |
| Control risk | Intervention risk | |||||
| Usual care | ECMO | |||||
| Mortality (pooled) | 517 per 1000 | 324 per 1000 (264 to 408) | RR 0.64 (0.51 to 0.79) | 505 (three studies) | +--- VERY LOW Due to serious risk of bias and serious indirectness | Includes data from two quasirandomised trials of patients with influenza A H1N1 |
| Adverse event: bleeding | 0 per 1000 | 250 per 1000 | RR 26.02 (3.68 to 184.16) | 249 (two studies) | +--- VERY LOW Due to serious risk of bias and serious indirectness | |
ARDS, acute respiratory distress syndrome; ECMO, extracorporeal membrane oxygenation.