Performance characteristics of the severity scoring systems using 30-day mortality as the outcome measure
| Score (n) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | NLR | PLR |
| CURB65 ≥2 (851) | 85.0 | 40.1 | 26.0 | 91.5 | 0.37 | 1.42 |
| CURB65 ≥3 (456) | 56.9 | 70.1 | 32.5 | 86.9 | 0.61 | 1.94 |
| Lac-CURB-65 ≥moderate (1009) | 96.4 | 20.3 | 24.1 | 95.6 | 0.18 | 1.21 |
| Lac-CURB-65 high (503) | 65.9 | 64.9 | 33 | 87.9 | 0.53 | 1.88 |
| qSOFA* (317) | 40.3 | 79.9 | 33.4 | 84.3 | 0.75 | 2.01 |
| NEWS ≥medium (997) | 79 | 39.9 | 23.4 | 89.1 | 0.53 | 1.31 |
| NEWS high (560) | 57.9 | 68.5 | 30.0 | 87.5 | 0.61 | 1.84 |
*Cut-off value for qSOFA was ≥2.
NEWS, National Early Warning Score; NLR, negative likelihood ratio;NPV, negative predictive value;PLR, positive likelihood ratio;PPV, positive predictive value;qSOFA, quick Sequential (Sepsis-related) Organ Failure Assessment.