Baseline demographics n=27/476 | |
Number with MRI brain imaging for review | 16 |
Age (mean, years) | 37.1 (23–51) |
Male | 9 (56.3%) |
Genotype | |
F508del homozygous | 9 (56.25%) |
F508del+ another mutation | 3 (18.75%) |
Other mutations | 2 (12.5%) |
Heterozygote (F508del/unknown*) | 2 (12.5%) |
Lung function | |
Mean percentage predicted FEV1 (forced expiratory volume in 1 s) | 43.3% (22-83) |
Mean percentage predicted FVC (forced vital capacity) | 59.6% (39-93) |
*Both patients presenting prior to extended genotype testing but with elevated sweat chloride levels and classic CF symptoms.
CF, cystic fibrosis.