Table 2

Dyspnoea-12 measurement properties for the Swedish Dyspnoea-12

Validation tests for Dyspnoea-12All patientsPatients with COPD
Patients with non-COPD
Internal consistency, Cronbach’s alpha
 Physical domain score0.8430.8300.846
 Affective domain score0.8000.8080.797
Test–retest reliability over 2 weeks, ICC (95% CI)
 Total0.81 (0.70 to 0.88)0.81 (0.43 to 0.94)0.81 (0.69 to 0.89)
 Physical domain score0.78 (0.67 to 0.86)0.79 (0.49 to 0.93)0.78 (0.65 to 0.87)
 Affective domain score0.75 (0.62 to 0.84)0.73 (0.32 to 0.90)0.76 (0.62 to 0.85)
Concurrent validity, Pearson’s correlation coefficients of Dyspnoea-12 total score with:
 FEV1 % of predicted−0.297−0.397−0.266
 CAT l0.6160.5370.658
 HADS total0.3290.3700.310
 HADS anxiety0.4490.5350.419
 HADS depression−0.094−0.247−0.062
 Dyspnoea-12 physical score with:
 FEV1 %pred−0.351−0.435−0.324
 HADS total0.2620.2810.249
 HADS anxiety0.3420.3430.338
 HADS depression−0.053−0.083−0.057
 D-12 affective score with:
 FEV1 %pred−0.225−0.354−0.197
 HADS total0.3580.3480.356
 HADS anxiety0.5130.5990.483
 HADS depression−0.147−0.083−0.082
  • Measurement properties for all patients and for patients with COPD or other conditions as main cause of breathlessness. Test–retest reliability was analysed between 2 weeks and baseline in people who rated their breathlessness as unchanged.

  • CAT, COPD Assessment Test; COPD, chronic obstructive pulmonary disease;EQ-5D-5L, Euro-QoL-5 Dimensions-5 Levels; FACIT-Fatigue, Functional Assessment of Chronic Illness Therapy-Fatigue; FEV1%pred, forced expiratory volume in 1 s in percentage of predicted value; HADS, Hospital Anxiety and Depression Scale; ICC, intraclass correlation coefficient; mMRC, modified Medical Research Council.