Table 3

Univariate and multivariate analysis of factors associated with death among n=342 with primary lung cancer; using Cox proportional hazards regression

Factors†Total‡ (n=342)Died§ (n=273)pdays† (179 151)Rate (95% CI)/1000 pdaysUnivariate analysisMulitivariate analysis
HR (95% CI)P value*aHR (95% CI)P value*
CAO
 No297229169 7371.35 (1.19 to 1.53)1<0.00110.001
 Yes454494144.67 (3.48 to 6.28)2.52 (1.81 to 3.50)1.78 (1.27 to 2.48)
Age-group/years
 ≤60524424 4371.80 (1.34 to 2.42)10.0210.003
 61–701087769 8911.10 (0.88 to 1.38)0.72 (0.50 to 1.04)0.70 (0.48 to 1.02)
 71–801209360 2011.54 (1.26 to 1.89)0.93 (0.65 to 1.34)0.96 (0.66 to 1.38)
 ≥81625924 6222.40 (1.86 to 3.09)1.25 (0.85 to 1.85)1.34 (0.90 to 1.99)
Gender
 Female16312693 4651.35 (1.13 to 1.60)10.1410.48
 Male17914785 6861.71 (1.46 to 2.02)1.19 (0.94 to 1.52)1.09 (0.86 to 1.39)
Stage ≥IIIB
 No15496128 6980.75 (0.61 to 0.91)1<0.0011<0.001
 Yes18817750 4533.51 (3.03 to 4.07)3.69 (2.85 to 4.78)3.52 (2.70 to 4.60)
  • *P values from the likelihood ratio test.

  • †Total person days=179 151 unless otherwise indicated.

  • ‡Denominator=342 unless otherwise indicated.

  • §Number that died=273 unless otherwise indicated.

  • aHR, adjusted hazard ratio; CAO, central airway obstruction on index CT scan; pdays, person days.