Table 5

Direct comparison of the ‘Reduced’ HUNT model against NELSON criteria, for the same number of individuals (n=1668), on the control group of DLCST. The HUNT model shows increased predictive performance in all metrics (sensitivity, specificity, PPV, NPV)

LC (N)Without LC (N)Total (N)Predictive value
Population521 9471999
‘Reduced’ HUNT*
 Criteria positive50 TP (3.00%)1618 FP (97.00%)1668†PPV 3.00%
 Criteria negative2 FN (0.60%)329 TN (99.40%)331NPV 99.40%
 Sensitivity96.15%
 Specificity16.90%
NELSON‡
 Criteria positive47 TP (2.82%)1621 FP (97.18%)1668*PPV 2.82%
 Criteria negative5 FN (1.51%)326 TN (98.45%)331NPV 98.45%
 Sensitivity90.38%
 Specificity16.74%
  • ‘Reduced’ HUNT model.

  • *‘Reduced’ HUNT model criteria.

  • †The number of those picked by the NELSON, but with the top risk score by the ‘Reduced’ HUNT model.

  • ‡NELSON criteria age 50–75, >15 cigarettes a day >25 years, or >10 cigarettes a day >30 years, both with 10 or less years quit time.

  • FN, false negative; FP, false positive; NPV, negative predictive value; PPV, positive predictive value; TN, true negative; TP, true positive.