Variable | PLCO high risk | PLCO low risk | All | P value |
Number of attendees (%) | 35 (8.0) | 403 (92.0) | 438 (100.0) | – |
Mean age (±SD), y | 64.4 (6.1) | 49.4 (8.5) | 50.6 (9.3) | <0.001 |
Sex (%) | 0.339* | |||
Female | 6 (17.1) | 98 (24.3) | 104 (23.7) | |
Male | 29 (82.9) | 305 (75.7) | 334 (76.3) | |
Body mass index (mean±SD) | 27.3 (5.6) | 28.1 (4.2) | 28.1 (4.3) | 0.286 |
Smoking status (%) | 0.031* | |||
Former | 8 (22.9) | 167 (41.4) | 175 (40.0) | |
Current | 27 (77.1) | 236 (58.6) | 263 (60.0) | |
Pack-years (median; quartile) | 47 (34; 60) | 17.5 (8; 30) | 21 (9; 30) | <0.001† |
Personal cancer | 0.009‡ | |||
Negative | 29 (85.3) | 391 (96.8) | 420 (95.9) | |
Positive | 5 (14.7) | 13 (3.2) | 18 (4.1) | |
COPD, emphysema, bronchitis | <0.001‡ | |||
Negative | 15 (44.1) | 345 (85.4) | 360 (82.2) | |
Positive | 19 (55.9) | 59 (14.6) | 78 (17.8) | |
Family history of lung cancer | 0.444‡ | |||
Negative | 34 (97.1) | 397 (98.5) | 431 (98.4) | |
Positive | 1 (2.9) | 6 (1.5) | 7 (1.6) | |
Education (n=438) | <0.001§ | |||
Less than high school | 5 (14.3) | 4 (1.0) | 9 (2.1) | |
High school | 15 (42.9) | 36 (8.9) | 51 (11.6) | |
College | 11 (31.4) | 147 (36.5) | 158 (36.1) | |
Postgraduate | 4 (11.4) | 216 (53.6) | 220 (50.2) | |
Race | 0.838§ | |||
White | 33 (94.3) | 371 (92.1) | 404 (92.2) | |
Black | 1 (2.9) | 11 (2.7) | 12 (2.7) | |
Hispanic | 0 (0.0) | 4 (1.0) | 4 (0.9) | |
Asian | 1 (2.9) | 17 (4.2) | 18 (4.1) |
T-test.
*χ2 test.
†Mann-Whitney U test.
‡Fisher’s exact test.
§Likelihood ratio test.
COPD, chronic obstructive pulmonary disease; NLST, National Lung Screening Trial.