Table 2

Characteristics of individuals, stratified by PLCOm2012 6-year lung cancer risk

VariablePLCO high riskPLCO low riskAllP value
Number of attendees (%)35 (8.0)403 (92.0)438 (100.0)
Mean age (±SD), y64.4 (6.1)49.4 (8.5)50.6 (9.3)<0.001
Sex (%)0.339*
 Female6 (17.1)98 (24.3)104 (23.7)
 Male29 (82.9)305 (75.7)334 (76.3)
Body mass index (mean±SD)27.3 (5.6)28.1 (4.2)28.1 (4.3)0.286
Smoking status (%)0.031*
 Former8 (22.9)167 (41.4)175 (40.0)
 Current27 (77.1)236 (58.6)263 (60.0)
Pack-years (median; quartile)47 (34; 60)17.5 (8; 30)21 (9; 30)<0.001†
Personal cancer0.009‡
Negative29 (85.3)391 (96.8)420 (95.9)
Positive5 (14.7)13 (3.2)18 (4.1)
COPD, emphysema, bronchitis<0.001‡
Negative15 (44.1)345 (85.4)360 (82.2)
Positive19 (55.9)59 (14.6)78 (17.8)
Family history of lung cancer0.444‡
 Negative34 (97.1)397 (98.5)431 (98.4)
 Positive1 (2.9)6 (1.5)7 (1.6)
Education (n=438)<0.001§
 Less than high school5 (14.3)4 (1.0)9 (2.1)
 High school15 (42.9)36 (8.9)51 (11.6)
 College11 (31.4)147 (36.5)158 (36.1)
 Postgraduate4 (11.4)216 (53.6)220 (50.2)
Race0.838§
 White33 (94.3)371 (92.1)404 (92.2)
 Black1 (2.9)11 (2.7)12 (2.7)
 Hispanic0 (0.0)4 (1.0)4 (0.9)
 Asian1 (2.9)17 (4.2)18 (4.1)
  • T-test.

  • 2 test.

  • †Mann-Whitney U test.

  • ‡Fisher’s exact test.

  • §Likelihood ratio test.

  • COPD, chronic obstructive pulmonary disease; NLST, National Lung Screening Trial.