Table 2

OR for treatment failure of first exacerbation among COPD outpatients in different age groups

Doxycycline (n=2261)Reference (n=4039)Crude OR
(95% CI)
Adjusted OR*
(95% CI)
Treatment failure (n, %)
Overall354 (15.7)640 (15.8)0.99 (0.86 to 1.14)0.97 (0.84 to 1.12)
Subgroups
55–6599 (14.8)166 (12.9)1.18 (0.90 to 1.54)1.17 (0.89 to 1.53)
65–75116 (15.8)196 (14.4)1.11 (0.87 to 1.43)1.11 (0.86 to 1.42)
≥75139 (16.1)278 (19.9)0.78 (0.62 to 0.97)0.77 (0.62 to 0.97)
  • *Adjusted for age, SABA, LABA/ICS, theophylline.

  • COPD, chronic obstructive pulmonary disease.