OR for treatment failure of first exacerbation among COPD outpatients in different age groups
| Doxycycline (n=2261) | Reference (n=4039) | Crude OR (95% CI) | Adjusted OR* (95% CI) | |
| Treatment failure (n, %) | ||||
| Overall | 354 (15.7) | 640 (15.8) | 0.99 (0.86 to 1.14) | 0.97 (0.84 to 1.12) |
| Subgroups | ||||
| 55–65 | 99 (14.8) | 166 (12.9) | 1.18 (0.90 to 1.54) | 1.17 (0.89 to 1.53) |
| 65–75 | 116 (15.8) | 196 (14.4) | 1.11 (0.87 to 1.43) | 1.11 (0.86 to 1.42) |
| ≥75 | 139 (16.1) | 278 (19.9) | 0.78 (0.62 to 0.97) | 0.77 (0.62 to 0.97) |
*Adjusted for age, SABA, LABA/ICS, theophylline.
COPD, chronic obstructive pulmonary disease.