Table 3

Summary of acute respiratory infection (ARI) events during infancy (≤1 year) in study subjects (N=225)

ARI eventsn (%)
Total ARI episodes470
 Upper respiratory tract infections (URTIs)427 (90.8)
 Lower respiratory tract infections (LRTIs)43 (9.2)
Number of infants who had ARI173 (76.9)
 URTI130/173 (75.1)
 LRTI43/173 (24.9)
Number of children with wheezing during ARI57 (25.4)
Infants with recurrent ARI (≥2)132/225 (58.6)
Number of infants who needed hospitalisation (n=27)27/225 (12)
With URTI6/27 (22.2)
With LRTI21/27 (77.8)
Number of infants with viral ARI (n=154)154/173 (68.4)
 URTI114/154 (74)
 LRTI40/154 (26)
Frequency of detected viruses during ARI episodes (n=380)*
 Rhinovirus (RV)152/380(40)
 Respiratory syncytial virus (RSV)77/380 (20.3)
 Parainfluenza75/380 (19.7)
 Human coronavirus63/380 (16.5)
 Human metapneumovirus37/380 (9.7)
 Others viruses100/380 (26.3)
Aetiology of LRTI episodes (n=43)
Viruses40/43 (93)
 RV28/40 (70)
 RSV23/40 (57.5)
Evidence of bacterial infection32/43 (74.5)
Streptococcal pneumoniae9/32 (28.2)
Chlamydia pneumoniae5/32 (15.6)
Mycoplasma pneumoniae1/32 (3.1)
 Only raised procalcitonin level (>0.5 ng/mL)17/32 (53.2)
Mixed bacterial and viral Infection29/43 (67.4)
  • *In 110 ARI episodes, more than one virus was detected.