Table 1

Study visit schedule

Assessment	Baseline	Period 1				Washout/ second visit	Period 2				Final visit
Assessment	D0	D1	D14 (±1)	D26	D28	D29–31 (±3)	D32 (±3)	D46 (±1)	D58	D60	D61 (±3)
Blood collection (biomarker analysis, safety blood tests)	X	First dose of study drug/placebo for period 1	X		Final dose of study drug/placebo for period 1	X	First dose of study drug/placebo for period 2	X		Final dose of study drug/placebo for period 2	X
DXA	X					X					X
Weight	X					X					X
ECG	X					X					X
QoL: FACT-L and ACS	X					X					X
Accelerometer	X*			X*					X*
24 hours dietary recall	X					X					X
Assessment of toxicity	X		X			X		X			X

*Wear accelerometer.
ACS, Anorexia Cachexia Scale; DXA, dual X-ray absorptiometry; FACT-L, Functional Assessment of Cancer Therapy—Lung; QoL, quality of life.