Basal values for haemodynamic and blood sample parameters
| Parameter | Substitute | |||
| Rat RBC (n=5) | Low-P50 HbV (n=8) | HbV (n=5) | HSA (n=8) | |
| Body weight (g) | 306±82 | 356±64 | 317±28 | 318±24 |
| Haematocrit (%) | 33.2±2.1 | 34.7±2.8 | 33.9±1.6 | 35.6±3.3 |
| Haemoglobin (g/L) | 112±9 | 117±10 | 113±6 | 123±15 |
| MAP (mm Hg) | 83±11 | 92±14 | 78±13 | 88±8 |
| HR (beats/min) | 230±34 | 235±24 | 240±14 | 271±15 |
| PaO2 (Torr) | 63.2±5.9 | 61.9±7.9 | 66.8±11.5 | 60.5±6.5 |
| PaCO2 (Torr) | 45.2±4.2 | 43.7±5.2 | 42.9±1.5 | 41.6±8.7 |
| pH | 7.351±0.046 | 7.375±0.030 | 7.351±0.023 | 7.388±0.079 |
| BE (mmol/L) | −0.6±2.3 | 0.3±2.7 | −2.0±1.4 | −0.5±2.4 |
| sO2 (%) | 90.2±3.0 | 89.9±4.3 | 91.0±3.7 | 89.8±3.5 |
| CaO2 (mL/dL) | 13.7±1.1 | 14.3±1.1 | 14.0±0.9 | 15.0±1.5 |
| Lactate (mmol/L) | 0.30±0.28 | 0.25±0.31 | 0.19±0.26 | 0.50±0.36 |
| Renal cortical PtO2 (mm Hg) | 26.4±2.3 | 27.1±2.2 | 27.4±1.5 | 27.4±2.1 |
BE, base excess; CaO2, arterial oxygen content; HbV, haemoglobin vesicle; low-P50 HbV, haemoglobin vesicle with high oxygen affinity; HR, heart rate; HSA, human serum albumin; MAP, mean arterial pressure; PaCO2, partial pressure arterial carbon dioxide; PtO2, partial pressure of tissue oxygen; RBC, red blood cell; sO2, arterial oxygen saturation.