Table 2

Factors influencing the decision to initiate therapy for NTM-PD

Host factorsMycobacterial factorsEnvironmental factors
Severity of respiratory and constitutional symptoms (eg, cough, sputum production, breathlessness, fatigue and malaise)Virulence/pathogenicity (usually identified from mycobacterial speciation)Promotion of NTM persistence (eg, through the use of inhaled steroids)
ComorbiditiesDrug resistance profile (note: there is usually only limited information available)Ongoing exposure to mycobacteria
Degree of lung damage (severity and/or extent of disease)
  • NTM, non-tuberculous mycobacteria; NTM-PD, non-tuberculous mycobacterial pulmonary disease.