Table 4

Side effects associated with the multidrug-resistant tuberculosis treatment

Side effects (n=90)Offending drugsn (%)
ArthralgiaLevofloxacin, pyrazinamide63 (70)
HypothyroidismEthambutol50 (55.6)
Gastrointestinal symptomsEthambutol, ethionamide41 (45.6)
Dizziness/vertigoKanamycin, levofloxacin20 (22.2)
Hearing lossKanamycin6 (6.7)
Clinical signs of hepatotoxicityPyrazinamide, ethionamide2 (2.2)
Alopecia1 (1.1)
Central nervous system
 Sleep disturbances/minor moodCycloserine, levofloxacin15 (16.7)
 DepressionCycloserine5 (5.6)
 PsychosisCycloserine4 (4.4)
 Suicidal thoughtsCycloserine, levofloxacin2 (2.2)