Unadjusted analysis | Adjusted analysis | ||||||
Estimate | 95% CI | P value | Estimate | 95% CI | P value | ||
Hospital admissions | IRR | 0.93 | 0.88 to 0.99 | 0.018 | 0.93 | 0.88 to 0.99 | 0.020 |
ISWT (m) | Slope | 8.05 | 2.54 to 13.56 | 0.005 | NA | ||
ESWT (s) | Slope | 43.68 | 18.41 to 68.95 | 0.001 | 46.58 | 26.65 to 66.50 | 0.000 |
CAT (points) | Slope | 0.15 | −0.35 to 0.65 | 0.55 | −0.08 | −0.46 to 0.30 | 0.68 |
Hospital admissions at 12-month follow-up. ISWT, ESWT and CAT at 2-month follow-up. ISWT was not adjusted. ESWT was adjusted for pack-years and smoking status. CAT was adjusted for BMI and CAT at baseline. ISWT, ESWT and CAT were analysed with linear regression.
Hospital admissions were analysed with negative binomial regression and adjusted for age, FEV1, CAT and MRC at baseline.
Fit parameters for each model (McFadden’s R2): Hospital admissions: crude model R2=0.02 and adj. model R2=0.08. ISWT: crude model R2=0.12. ESWT: crude model R2=0.18 and adj. model R2=0.41. CAT: crude model R2=0.01 and adj model R2=0.30.
CAT, COPD Assessment Test; ESWT, endurance shuttle walk test; ISWT, incremental shuttle walk test; MRC, Medical Research Council dyspnoea scale; NA, not applicable.