Demographic, clinical and laboratory predictors of intubation using multivariable logistic regression
Univariate analysis (OR) | P value | Multivariate analysis (OR) | P value | |
Age (years) | ||||
≤65 | 1 | 0.31 | ||
>65 | 1.5 | |||
BMI | ||||
≤30 | 0.57 | |||
>30 | 0.79 | |||
Smoking | ||||
No | 1 | 0.32 | ||
Yes | 1.52 | |||
Race | ||||
Non-black | 1 | 0.72 | ||
Black | 0.87 | |||
Comorbidities | ||||
Heart disease | 1.48 | 0.41 | 2.59 | 0.047 |
Lung disease | 1.79 | 0.19 | ||
Diabetes | 0.91 | 0.83 | ||
HTN | 2.1 | 0.07 | ||
CKD | 2.91 | 0.01 | ||
Haemodialysis | 1.49 | 0.57 | ||
No comorbidity | 1 | 2.7 | 0.11 | |
Any comorbidity | 3.51 | 0.03 | ||
Laboratory markers | ||||
Ferritin <400 | 1 | 0.79 | ||
(ng/mL) ≥400 | 0.89 | |||
D-dimer <1000 | 1 | 0.37 | ||
(ng/mL) ≥1000 | 1.47 | |||
AST <105 | 1 | 0.53 | ||
(U/L) ≥105 | 1.6 | |||
AST <180 | 1 | 0.26 | ||
(U/L) ≥180 | 0.29 | |||
Triglycerides <300 | 1 | 0.07 | ||
(mg/dL) ≥300 | 4.81 | |||
Fibrinogen >450 | 1 | 0.007 | 3.02 | 0.027 |
(mg/dL) ≤450 | 3.53 | |||
Abs Lymph Ct ≥1 | 1 | 0.26 | ||
(K/mm3) <1 | 0.62 | |||
LDH ≤350 | 1 | 0.18 | ||
(U/L) >350 | 1.85 | |||
CRP <6 | 1 | 0.22 | ||
(mg/dL) ≥6 | 0.58 | |||
Cumulative laboratory score (1 point per abnormality) | ||||
<3 | 1 | 0.36 | ||
≥3 | 1.5 | |||
SF ratio | ||||
≥100 | 1 | 0.05 | 2.61 | 0.04 |
<100 | 2.3 |
Abs Lymph Ct, absolute lymphocyte count; ALT, alanine aminotransferase; AST, aspartate transaminase; BMI, body mass index; CKD, chronic kidney disease; CRP, C reactive protein; HTN, hypertension; LDH, lactate dehydrogenase; SF ratio, saturation to fraction ratio.