Laboratory findings among patients infected with SARS-CoV-2 admitted to two hospitals in Uganda
Characteristic | All | Mulago National Specialised Hospital/−HCQ | Entebbe Regional Referral Hospital/+HCQ | P value |
Laboratory | ||||
White cell count/mm3 | n=47 | n=21 | n=26 | |
Median (IQR) | 5.1 (4.2−6.2) | 5.0 (4.2−6.3) | 5.1 (4.5−6.1) | 0.473* |
Distribution, n (%) | ||||
≥10 000/mm3 | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
4001−<10 000/mm3 | 42 (89.4) | 17 (81.0) | 25 (92.1) | 0.158† |
≤4000/mm3 | 5 (10.6) | 4 (19.0) | 1 (3.9) | |
Neutrophil count | n=45 | n=19 | n=26 | |
Median (IQR)/mm3 | 2 (2−2) | 2 (1−2) | 2 (2−2) | 0.092* |
Distribution, n (%) | ||||
≤1500/mm3 | 7 (15.6) | 5 (26.3) | 2 (7.7) | 0.114† |
Lymphocyte count | n=45 | n=19 | n=26 | |
Median (IQR)/mm3 | 2.3 (1.8−2.9) | 2.4 (1.4−2.9) | 2.3 (2.0−2.9) | 0.340* |
Distribution, n (%) | ||||
≤1500/mm3 | 5 (11.1) | 5 (26.3) | 0 (0.0) | 0.010† |
Platelets per mm3 | n=19 | n=18 | n=1 | |
Median (IQR) | 227 (121−275) | 224.5 (121−275) | 232 | 0.855* |
Distribution, n (%) | ||||
<150 000/mm3 | 5 (26.3) | 5 (27.8) | 0 (0.0) | >0.999† |
Haemoglobin (g/L) | n=19 | n=18 | n=1 | |
Median (IQR) | 1.47 (1.34−1.60) | 1.47 (1.34−1.57) | 1.62 | 0.273* |
Distribution, n (%) | ||||
≤1.0 g/L | 2 (10.5) | 2 (11.1) | 0 (0.0) | >0.999† |
Aspartate aminotransferase >40 U/L, n/N (%) | 4/47 (8.5) | 3/18 (16.7) | 1/29 (3.5) | 0.150† |
Alanine aminotransferase >40 U/L, n/N (%) | 6/47 (12.8) | 5/18 (27.8) | 1/29 (3.5) | 0.025† |
LDH≥250 U/L, n/N (%) lactate | 0/11 (0.0) | 0/11 (0.0) | ||
Creatinine ≥133 μmol/L, n/N (%) | 0/48 (0.0) | 0/19 (0.0) | 0/29 (0.0) | – |
Troponin, median (IQR) | 0.1 (0.1–0.1) | 0.1 (0.1–0.1) | 0.1 (0.1–0.1) | 0.532* |
Total bilirubin >17.1 μmol/L, n/N (%) | 2/15 (13.3) | 2/14 (14.3) | 0/1 (0.0) | >0.999† |
Total bilirubin, median (IQR) | 2.5 (0–12.9) | 2.4 (0–11.7) | 13.8 | 0.232* |
C reactive protein ≥10 mg/L, n/N (%) | 6/49 (12.2) | 5/24 (20.8) | 1/25 (4.0) | 0.098† |
Median (IQR) | 1.7 (0.5–8.1) | 4.0 (1.8–9.7) | 0.5 (0.5–1.4) | <0.001* |
Procalcitonin ng/mL | n=49 | n=24 | n=25 | |
Median (IQR) | 0.1 (0.1–0.12) | 0.1 (0.1–0.12) | 0.1 (0.1–0.13) | 0.614* |
Lactate dehydrogenase | n=49 | n=24 | n=25 | |
Median (IQR) | 330 (287–402) | 318 (244–385) | 330.5 (295.5–402.5) | 0.282† |
*Wilcoxon rank-sum test.
†Fisher’s exact test.
LDH, lactate dehydrogenase.