Table 3

Description of observational studies with an ocular disorder as an outcome

Primary authorSmeeth29
Year2003
Study designCase-control study
Length of study/follow-upAt least 180 days
PopulationUK primary care electronic medical records (Clinical Practice Research Datalink)
Sample size15 479 people with cataract and 15 479 controls
Age range40 years +
Asthma diagnosis definitionN/A
ICS type (drug/name)Beclomethasone, budesonide, fluticasone
Control/comparisonGeneral population matched controls with no ICS ever
Primary outcomeCataracts
Secondary outcomes of studyN/A
Statistical analysisConditional logistic regression
Adjusted covariatesOnly OCS and consultation rate for the asthma effect estimate
Crude results1.52 (95% CI 1.41 to 1.65)
Adjusted results1.05 (95% CI 0.95 to 1.16)
  • ICS, inhaled corticosteroid; OCS, oral corticosteroids.