Univariable and multivariable postadjusted logistic regression analyses: association between patient characteristics and severity of COVID-19
| Covariate | Univariable logistic regression | Final multivariable postadjusted logistic regression model | ||
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Constant | – | – | 0.000 | 0.001 |
| Male gender | 2.28 (0.95 to 5.48) | 0.064 | 0.90 (0.23 to 3.56) | 0.884 |
| Age | 1.02 (0.98 to 1.06) | 0.288 | 1.01 (0.96 to 1.06) | 0.684 |
| Metabolic syndrome | 1.56 (0.63 to 3.90) | 0.339 | 0.70 (0.21 to 2.19) | 0.506 |
| Use of antihypertensives* | 0.58 (0.21 to 1.63) | 0.303 | – | – |
| Hypertriglyceridemia* | 1.13 (0.45 to 2.83) | 0.802 | – | – |
| Low HDL-C* | 2.63 (0.67 to 10.42) | 0.168 | – | – |
| Hyperglycaemia* | 1.79 (0.70 to 4.58) | 0.225 | – | – |
| Abdominal adiposity* | 3.50 (1.23 to 9.93) | 0.019 | – | – |
| Waist–hip ratio | 1.11 (1.05 to 1.18) | 0.001 | 1.11 (1.02 to 1.20) | 0.014 |
| BMI | 1.11 (1.02 to 1.21) | 0.016 | 1.11 (1.00 to 1.23) | 0.043 |
| Post hoc power | – | 0.85 | ||
*Metabolic syndrome criterion. Cut-off values: high triglycerides (>1.7 mmol/L), low HDL-C (<1 mmol/L in male, <1.3 mmol/L in female), hyperglycaemia ≥7.8 mmol/L and/or drug treatment for elevated blood glucose, abdominal adiposity (male ≥102 cm, female ≥88 cm). Statistically significant p-values are bold.
BMI, body mass index; HDL-C, high-density lipoprotein cholesterol.