Variable | Number of patients for whom data were available | Data summary |

Age at diagnosis (years) (mean±SD) | 100 | 73.2±7.8 |

Gender | 100 | |

Male (n (%)) | 85 (85%) | |

Female (n (%)) | 15 (15%) | |

Weight (kg) (mean±SD) | 70 | 74.8±16.8 |

BMI (kg/m^{2}) (mean±SD) | 48 | 26.0±4.9 |

Asbestos exposure | 89 | |

Yes (n (%)) | 69 (78%) | |

No (n (%)) | 20 (22%) | |

Smoking status | 94 | |

Non-smoker (n (%)) | 25 (27%) | |

Ex-smoker (n (%)) | 57 (61%) | |

Current smoker (n (%)) | 12 (13%) | |

Performance status (PS) | 95 | |

0 (n (%)) | 24 (25%) | |

1 (n (%)) | 43 (45%) | |

2+ (n (%)) | 28 (29%) | |

Comorbidities | 98 | |

Respiratory comorbidity (n (%)) | 17 (17%) | |

Non-respiratory comorbidity (n (%)) | 69 (70%) | |

Total no of comorbidities | ||

0 (n (%)) | 24 (24%) | |

1 (n (%)) | 39 (40%) | |

2+ (n (%)) | 35 (36%) | |

Dyspnoea (n (%)) | 99 | 84 (85%) |

Chest pain (n (%)) | 99 | 43 (43%) |

Cough (n (%)) | 99 | 55 (56%) |

Weight loss (n (%)) | 99 | 51 (52%) |

Loss of appetite (n (%)) | 99 | 45 (45%) |

Night sweats (n (%)) | 99 | 13 (13%) |

Fever (n (%)) | 99 | 2 (2%) |

Histological subtype | 94 | |

Epithelioid (n (%)) | 63 (67%) | |

Sarcomatoid (n (%)) | 21 (22%) | |

Unclassified (n (%)) | 10 (11%) | |

Malignant cells (cytology) (n (%)) | 65 | 18 (28%) |

Hb g/dL (mean±SD) | 99 | 13.3±1.7 |

RDW % (median (IQR)) | 99 | 14.1 (13.2 to 15.3) |

PLT ×10^{9}/L (mean±SD) | 99 | 340±114 |

WCC ×10^{9}/L (median (IQR)) | 99 | 9.2 (8.1 to 11.7) |

NLR (median (IQR)) | 99 | 5.2 (3.4 to 7.6) |

CRP mg/L (median (IQR)) | 66 | 48 (15 to 80) |

Urea mmol/L (median (IQR)) | 98 | 4.7 (4.0 to 6.2) |

Na mmol/L (mean±SD) | 98 | 136±3 |

K mmol/L (mean±SD) | 96 | 4.4±0.4 |

Creatinine µmol/L (median (IQR)) | 98 | 81 (67 to 94) |

Total protein g/L (mean±SD) | 92 | 66.9±6.1 |

Albumin g/L (mean±SD) | 92 | 32.9±5.0 |

ALP IU/L* (median (IQR)) | 92 | 73 (56 to 92) |

Adjusted calcium mmol/L (median (IQR)) | 80 | 2.32 (2.26 to 2.39) |

Phosphate mmol/L (mean±SD) | 77 | 1.16±0.23 |

Pleural fluid protein g/L (mean±SD) | 49 | 43.7±8.9 |

Pleural fluid LDH IU/L* (median (IQR)) | 52 | 701 (488 to 1376) |

Categorical variables are summarised by the number and percentage. Continuous variables with a normal distribution are summarised by the mean and SD. Continuous variables with a skewed distribution are summarised by the median and IQR.

*International units per litre.