Table 2

Unadjusted correlation of baseline characteristics and disease severity with calprotectin serum levels in the three study groups

Calprotectin levelsHealthy controlsDerivation IPF cohortValidation IPF cohort
VariablesrP valuerP valuerP value
Sex, men0.030.810.15
Age, years0.170.39−0.020.91−0.160.20
BMI, kg/m20.500.0090.120.630.010.94
DLCO, % predicted0.310.12−0.530.007−0.230.06
FVC, % predicted0.120.560.020.90−0.130.29
FEV1, % predicted0.130.540.330.20−0.030.78
  • BMI, body mass index; CPI, Composite Physiological Index; DLCO, diffusing capacity for carbon monoxide; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; IPF, idiopathic pulmonary fibrosis; r, correlation coefficient.